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Effect of inhibitors of protein kinase CK2 on the activity of its catalytic subunits СК2α and СК2α´

Our paper dedicated to the study of effect of inhibitors of protein kinase CK2 on the activity of its catalytic subunits CK2α and CK2α′ has been published in Biotechnologia Acta...

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Pharmacophore approaches in protein kinase inhibitors design

Our review, dedicated to the analysis of pharmacophore models for protein kinase inhibitors design has been published in World Journal of Pharmacology.

Abstract: Protein kinases...

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The Prize of the President of Ukraine for Young Scientists, 2014

The scientific researcher of the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics of the NAS of Ukraine, Galyna Volynets, was awarded the prize of the...

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Collaboration with Department of Organic Chemistry of Oles Honchar Dnipropetrovsk National University has been started

The Department of Medicinal Chemistry has started a joint research project with the Department of Organic Chemistry of Oles Honchar Dnipropetrovsk National University. The main aim of the...

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Our research:

FGFR1 Inhibitors
Quinazolines Image
Quinazolines is another known class of RTK inhibitors that is widely...



 

CK2 Inhibitors
3-carboxy-4(1H)-quinolones Image
This CK2 inhibitors were revealed and evaluated to be a CK2 inhibitors after...



 

ASK1 Inhibitors
Evaluation of 2-Thioxo-thiazolidin-4-ones Derivatives as Inhibitors of ASK1 Image
In order to discover novel ASK1 inhibitors we have performed screening program,...



 

Fluorescent Probes
Fluorescent detection of partially denatured conformation of beta-lactoglobuline Image
The native state of many proteins is known to be only marginally stable,...



 

Molecular Design
Molecular Design Image
Molecular Design Laboratory of Medicinal Chemistry Department carry out...



 

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