A note of caution on the role of halogen bonds for protein kinase/inhibitor recognition suggested by high- and low-salt CK2α complex structures

Tuesday, 28 July 2015

Our paper in collaboration with Institute of Biochemistry, University of Cologne (Germany), dedicated to the investigation of cocrystal structures of protein kinase CK2 with inhibitor...

Grant Project “Target-oriented search of aminoacyl-tRNA synthetase inhibitors with selective action toward causative agents of human infectious diseases” has been started

Tuesday, 30 June 2015

We have started working on project "Target-oriented search of aminoacyl-tRNA synthetase inhibitors with selective action toward causative agents of human infectious diseases" in...

Participation in the IX Young Scientists Conference, dedicated to the 160th anniversary of Kashchenko Mykola Feofanovych

Thursday, 28 May 2015

PhD student at the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics, Sergiy Starosyla, has attended the IX Young Scientists Conference, dedicated to...

Design, synthesis and biological evaluation of N-phenylthieno[2,3-d]pyrimidin-4-amines as inhibitors of FGFR1

Monday, 30 March 2015

Our paper dedicated to the development of novel class of inhibitors for protein kinase FGFR1 has been published in Bioorganic and Medicinal Chemistry.

Abstract: Fibroblast...

News and Events

A note of caution on the role of halogen bonds for protein kinase/inhibitor recognition suggested by high- and low-salt CK2α complex structures

Grant Project “Target-oriented search of aminoacyl-tRNA synthetase inhibitors with selective action toward causative agents of human infectious diseases” has been started

Participation in the IX Young Scientists Conference, dedicated to the 160th anniversary of Kashchenko Mykola Feofanovych

Design, synthesis and biological evaluation of N-phenylthieno[2,3-d]pyrimidin-4-amines as inhibitors of FGFR1

Our research:

FGFR1 Inhibitors

CK2 Inhibitors

ASK1 Inhibitors

Molecular Design

Fluorescent Probes