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Identification of novel small-molecular inhibitors of Staphylococcus aureus sortase A using hybrid virtual screening

Recently, the article dedicated to the development of Staphylococcus aureus sortase A inhibitors using the methods of molecular docking and pharmacophore screening has been...

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Identification of novel antistaphylococcal hit compounds targeting sortase A

Recently, the article dedicated to the development of Staphylococcus aureus sortase A inhibitors possessing antibacterial activity toward multidrug resistant strains has been...

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Discovery of novel antituberculosis agents among 3-phenyl-5-(1-phenyl-1H-[1,2,3]triazol-4-yl)-[1,2,4]oxadiazole derivatives targeting aminoacyl-tRNA synthetases

Recently, the article dedicated to the development of novel antituberculosis agents among 3-phenyl-5-(1-phenyl-1H-[1,2,3]triazol-4-yl)-[1,2,4]oxadiazoles targeting aminoacyl-tRNA...

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Dual targeted hit identification using pharmacophore screening

Recently, the article dedicated to the development of dual-targeted inhibitors of mycobacterial aminoacyl-tRNA synthetases using pharmacophore screening has been...

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Our research:

FGFR1 Inhibitors
Oxindoles Image
Oxindoles are known class of inhibitors of RTK, including FGFR1. We perform...



 

ASK1 Inhibitors
Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as Inhibitors of ASK1 Image
Virtual screening and biochemical screening allowed us to identify...



 

CK2 Inhibitors
4'-hydroxyflavones Image
The novel synthetic flavone inhibitors (4'-hydroxyflavones) were identified...



 

Molecular Design
Molecular Design Image
Molecular Design Laboratory of Medicinal Chemistry Department carry out...



 

Fluorescent Probes
Design of fluorescent dyes for biomedical applications Image
Search and development of novel highly efficient fluorescent probes for biology...



 

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